Actor Richard Dreyfuss went public with his battle with bipolar disorder in the 2006 documentary The Secret Life of the Manic Depressive. Like many with this condition, he's struggled with a cocaine addiction and went through rehab.
Applied art commercial art print illustration by Norman Duenas titled "A Butterfly Effect." I really love the artists combination of nature with the human figure/skull and the depiction of a clock. It gives a great sense of the passage of time.