Acute Intravascular Hemolytic (immune) Transfusion Reaction. Caused usually by clerical errors. ABO or other erythrocyte antigen-antibodies are mislabeled. Signs/symptoms: hemoglobinemia and heoglobinuria, fever, chills, anxiety, shock, DIC, dyspnea, chest pain, flank pain, nausea/vomiting, headache, pain at needle site and along venous track. Treatment: STOP transfusion, hydrate, support BP and respiration, induce diuresis, treat shock and DIC.