Alfredo Sauce is a fast and easy creamy sauce made with a simple combination of heavy whipping cream, Parmesan cheese, butter, flour and garlic. This recipe for Homemade Alfredo Sauce is my family's absolute favorite. Alfredo Sauce is a classic creamy pasta sauce that only takes about 15 minutes to make and features lots of Parmesan cheese. Serve it with pasta, chicken, shrimp, broccoli, breadsticks, and many other dishes.